DEPENDENCE OF NUCLEOSOME MECHANICAL STABILITY ON DNA MISMATCHES

Dependence of nucleosome mechanical stability on DNA mismatches

The organization of nucleosomes into chromatin and their accessibility are shaped by local DNA mechanics.Conversely, nucleosome positions shape genetic variations, which may originate from mismatches during replication and chemical modification of DNA.To investigate how DNA mismatches affect the mechanical stability and the exposure of nucleosomal

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Landslide Displacement Prediction Using Kernel Extreme Learning Machine with Harris Hawk Optimization Based on Variational Mode Decomposition

Displacement deformation prediction is critical for landslide disaster monitoring, as a good landslide displacement prediction system helps reduce property losses and casualties.Landslides in the Three Gorges Reservoir Area (TGRA) are affected by precipitation and fluctuations in reservoir water level, and displacement deformation shows a step-like

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